Identification of the cytochrome P450 enzymes involved in the N‐demethylation of sildenafil
Open Access
- 1 March 2001
- journal article
- research article
- Published by Wiley in British Journal of Clinical Pharmacology
- Vol. 51 (3), 239-248
- https://doi.org/10.1046/j.1365-2125.2001.00318.x
Abstract
Aims To characterize the cytochrome P450 (CYP) enzymes responsible for the N-demethylation of sildenafil to its main metabolite, UK-103 320, to investigate the potential inhibitory effects of silden...Keywords
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