Ebselen Protects Both Gray and White Matter in a Rodent Model of Focal Cerebral Ischemia
- 1 September 2001
- journal article
- other
- Published by Wolters Kluwer Health in Stroke
- Vol. 32 (9), 2149-2154
- https://doi.org/10.1161/hs0901.095725
Abstract
Background and Purpose— The neuroprotective efficacy of an intravenous formulation of the antioxidant ebselen has been comprehensively assessed with specific regard to conventional quantitative his...Keywords
This publication has 35 references indexed in Scilit:
- The Lipid Peroxidation By-product 4-Hydroxynonenal is Toxic to Axons and OligodendrocytesJournal of Cerebral Blood Flow & Metabolism, 2000
- Selenoorganic compound, ebselen, inhibits nitric oxide and tumor necrosis factor-? production by the modulation of Jun-N-terminal kinase and the NF-?b signaling pathway in rat Kupffer cellsJournal of Cellular Biochemistry, 2000
- Quantitative Assessment of Ischemic Pathology in Axons, Oligodendrocytes, and Neurons: Attenuation of Damage after Transient IschemiaJournal of Cerebral Blood Flow & Metabolism, 2000
- White matter ischaemiaBrain Research Reviews, 1999
- Rapid Alteration of Tau in Oligodendrocytes After Focal Ischemic Injury in the Rat: Involvement of Free RadicalsJournal of Cerebral Blood Flow & Metabolism, 1997
- The κ-opioid receptor expressed on the mouse lymphoma cell line R1.1 contains a sulfhydryl group at the binding siteEuropean Journal of Pharmacology: Molecular Pharmacology, 1994
- Ebselen is a specific inhibitor of LTB4-mediated migration of human neutrophilsInflammation Research, 1993
- Both NMDA and non-NMDA subtypes of glutamate receptors are concentrated at synapses on cerebral cortical neurons in cultureNeuron, 1991
- The anti-inflammatory activity of Ebselen but not thiols in experimental alveolitis and bronchiolitisInflammation Research, 1988
- Quantitative assessment of early brain damage in a rat model of focal cerebral ischaemia.Journal of Neurology, Neurosurgery & Psychiatry, 1987