THE EVALUATION OF ACTIVE RESISTANCE TO PNEUMOCOCCUS INFECTION IN RABBITS

Abstract

The responses of rabbits to infection with pneumococcus types I-III, by the intracutaneous route, varied between that which consists of a marked local reaction, high fever, and death, and that of an insignificant local reaction, no fever, and recovery. It is suggested that susceptibility and active resistance (immunity) should not be judged on the basis of survival or death of animal, but rather by severity of the infectious process which, for comparative purposes, the author divides into 7 main grades.