Eunuchoid Habitus Associated with Sickle-Cell Anemia and the Sickling Trait

Abstract

A study of 32 patients (13 [male] 19 [female]), 30 of whom had sickle cell anemia, is presented. One of the latter showed the sickling trait only, and another was anemic but sickling had not been demonstrated although her sister showed the phenomenon readily. The entire series of 32 subjects manifested abnormal statural development characterized by moderate to extreme degrees of eunuchoid asymmetry. Eunuchoid habitus may be associated with the sickling phenomenon although no data from other sources can be offered to support the postulate.