Studies in the biochemistry of micro-organisms

Abstract

A quantitative survey has been made of the Cl metabolism of 139 spp. or strains of moulds grown on Czapek-Dox 5% glucose soln. containing 0.5 g. per liter of KC1 as the sole source of Cl. The Cl metabolism of Caldariomyces fumago has been investigated in detail and has resulted in the isolation of a hitherto undescribed mould metabolic product. Caldariomycin, C5H8O2Cl2, which is probably 2,2-dichlorocyclopentane-l,3-diol. The same sp. also converts KBr, when present in the same medium in place of KC1. into organic Br-containing metabolic product-which have not yet been isolated in a pure state.