Dihydrocytochalasin B promotes adipose conversion of 3T3 cells
- 31 December 1986
- journal article
- research article
- Published by Wiley in Biology of the Cell
- Vol. 61 (3), 149-154
- https://doi.org/10.1111/j.1768-322x.1987.tb00581.x
Abstract
Differentiation of preadipose 3T3-F442A cells into adipose cells is accelerated by the addition of dihydrocytochalasin B. The effect of the drug on 3T3-C2 cells is more marked: these cells are practically unable to differentiate in the absence of H2CB but a long-term exposure to the drug enables the cells to accumulate lipid droplets in medium supplemented with fetal calf serum and insulin. During their differentition under these conditions the 3T3-C2 cells develop markers typical of adipose cells; glycerophosphate dehydrogenase, ATP-citrate lyase, fatty acid synthetase and glycerophosphate acyltransferase.This publication has 35 references indexed in Scilit:
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