The treatment of seborrheic dermatitis of the scalp at times plagues both patient and practitioner. There are many patients who remain free of the underlying erythema, scaling, and itching only as long as they are faithful and persistent in the use of ointments, lotions, and shampoos at daily, semiweekly, or weekly intervals. This can become a time-consuming problem, as well as a source of annoyance to the patient and those who live within the immediate orbit of these repetitive treatments, not only because of the frequent application, but because of the disagreeable odors of tars and sulfurs, not to mention the soiling of linens and furniture. The purpose of this communication is to report the results of a clinical trial of a medicament containing selenium disulfide1 in the treatment of seborrheic dermatitis of the scalp. Selenium, because of its relative closeness to sulfur in the periodic table, has