Multiple System Organ Failure
- 1 February 1980
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of Surgery
- Vol. 115 (2), 136-140
- https://doi.org/10.1001/archsurg.1980.01380020006003
Abstract
• Multiple system organ failure (MSOF) remains a principal cause of death after major operative procedures and/or severe trauma. We studied multiple parameters in 553 consecutive emergency surgical patients to determine the incidence of MSOF, the predisposing factors to MSOF, and the sequelae of MSOF. Thirty-eight patients had MSOF; mortality was 74% for these patients. Evaluation of multiple factors demonstrated that (1) MSOF is primarily due to infection, (2) the temporal sequence of organ failure is lung, liver, gastric mucosa, and kidney, and (3) MSOF is the most common fatal expression of uncontrolled infection. (Arch Surg115:136-140, 1980)This publication has 12 references indexed in Scilit:
- H2-RECEPTOR ANTAGONISTS AND ANTACIDS IN THE PREVENTION OF ACUTE GASTROINTESTINAL HÆMORRHAGE IN FULMINANT HEPATIC FAILUREThe Lancet, 1977
- REMOTE ORGAN FAILURE - VALID SIGN OF OCCULT INTRA-ABDOMINAL INFECTION1977
- MULTIPLE ORGAN FAILURE1977
- CLINICOPATHOLOGIC STUDY OF HEPATIC DYSFUNCTION FOLLOWING SHOCK1976
- Multiple, Progressive, or Sequential Systems FailureArchives of Surgery, 1975
- The Changing Pattern of Post-traumatic Respiratory Distress SyndromeAnnals of Surgery, 1975
- Postoperative Jaundice: Mechanism, Diagnosis and TreatmentSurgical Clinics of North America, 1975
- ACUTE RENAL FAILURE IN COMBAT INJURIESPublished by Wolters Kluwer Health ,1975
- Acute Renal Failure in General Surgical PatientsArchives of Surgery, 1971
- Defective oxidative metabolism of rat liver mitochondria in hemorrhagic and endotoxin shockAmerican Journal of Physiology-Legacy Content, 1971