The influence of the lyotropic series of anions on cation permeability

Abstract

Permeability of cat erythrocytes to Na and K is affected by the anions present. Anions at the dehydrating end of the lyotropic series, e.g. SO4, reduce K and increase Na permeability; anions at the hydrating end, e.g. CNS, have the reverse effect in both cases. Permeability to Na in presence of isotonic K salts of straight-chain fatty acids decreases slightly with each additional CH2 up to valerate. Caproate completely inhibits penetration of Na.