Fitness Cost of SCC mec and Methicillin Resistance Levels in Staphylococcus aureus
Open Access
- 1 June 2004
- journal article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 48 (6), 2295-2297
- https://doi.org/10.1128/aac.48.6.2295-2297.2004
Abstract
Transformation of a type I SCCmec element into Staphylococcus aureus yielded highly oxacillin-resistant transformants with a reduced growth rate. Faster-growing variants could again be selected at the cost of reduced resistance levels, demonstrating an inverse correlation between oxacillin resistance levels and growth rate.Keywords
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