A Simplified Micromethod for the Determination of the Acetylator Phenotype
- 1 January 1977
- journal article
- research article
- Published by Walter de Gruyter GmbH in cclm
- Vol. 15 (1-12), 329-332
- https://doi.org/10.1515/cclm.1977.15.1-12.329
Abstract
A simplified and rapid method is described for phenotyping sulfamethazine acetylation. Two hours after a test dose of sulfamethazine, free and total sulfamethazine are estimated in blood drawn either by capillary or venipuncture. The present method offers sharp segregation between slow and rapid acetylators, requires micro blood volumes drawn from finger- or ear-puncture, and is more convenient for population genetics survey as well as for clinical investigations.This publication has 12 references indexed in Scilit:
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