MECHANISMS OF BONE RESORPTION IN HUMAN METAPHYSEAL REMODELING

Abstract
Remodeling of the metaphysis was studied by roentgenographic and histologic examination of bones of newborn infants and by roentgenographic examination of lead-labeled bones of children. In contrast to the classical view, i.e., that longitudinal trabeculae are resorbed in the "cutting zone" by osteoclasts, it is shown that there is a symmetric conversion of trabeculae in the metaphysis and that the main or exclusive mechanism of bone resorption in this segment is osteolysis.