Antibody Production in Neonatal Chickens Following Injection of Adult Cells Mixed with Antigen in vitro.

Abstract

Summary Antibody production to Brucella abortus antigen was initiated in neonatal chicks by transfer of adult homologous hen spleen cells mixed with antigen in vitro. The studies indicate a wide variation in response and that a pathologic picture consisting primarily of splenomegaly is regularly associated with good agglutinin titers in the recipient.