Acetyl Coenzyme A Carboxylase: Filamentous Nature of the Animal Enzymes
- 5 December 1969
- journal article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 166 (3910), 1276-1278
- https://doi.org/10.1126/science.166.3910.1276
Abstract
Acetyl coenzyme A carboxylases purified from several animal tissues exist as enzymatically active polymeric filaments of high molecular weight and have simillar electron microscopic, hydrodynamic, and catalytic properties. These filaments reversibly dissociate into inactive protomers of uniform size. Their re-assembly into catalytically active filaments is promoted by the presence of an allosteric activator.Keywords
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