A thermo micro procedure for rapid extraction and direct application in thin-layer chromatography

Abstract

A simple thermo micro procedure is described for the separation of many substances from solid materials and the direct transfer of these substances to the starting point of a thin-layer chromatographic plate. The sample is introduced into a glass cartridge with a conical tip, and heated rapidly for a short time at a pre-set temperature. The emerging vapours are deposited as a spot on the thin-layer chromatographic plate, which is then chromatographed in the usual way. There are numerous variations of the standard procedure, thus extending the range of application, and this is demonstrated with examples from the fields of drug research, phytochemistry, analysis of food additives and residues, and from organic and inorganic chemistry.