Relevante Merkmale für die 5-Jahres-Prognose von Patienten mit schizophrenen und verwandten paranoiden Psychosen
- 1 May 1982
- journal article
- research article
- Published by Springer Nature in Archiv Fur Psychiatrie Und Nervenkrankheiten
- Vol. 231 (4), 305-322
- https://doi.org/10.1007/bf00345587
Abstract
In einer 5-Jahres-Katamnese an 81 Patienten mit schizophrenen oder ähnlichen paranoiden Psychosen konnten viele aus der Katamneseliteratur bekannte Prädiktoren bestätigt werden. Langdauernde berufliche Desintegration und psychiatrische Hospitalisierung vor Index-Aufnahme erwiesen sich, wie in den follow-up-Untersuchungen der Patienten der International Pilot Study of Schizophrenia (IPSS), als prognostisch besonders relevante Merkmale. Im Gegensatz zur follow-up der IPSS-Patienten, zeigt sich aber auch eine erhebliche prognostische Bedeutung psychopathologischer Merkmale insbesondere von Minussymptomatik. Durch schrittweise multiple Regressionsanalyse wurden für jedes „outcome“-Kriterium Kombinationen von 5 besten Prädiktoren ermittelt, die einen wesentlich größeren Varianzanteil erklärten, als einzelne Prädiktoren. In a 5 year follow-up study of 81 patients suffering from schizophrenic or similar psychoses many of the predictors known from the literature concerning the outcome of schizophrenia were confirmed. In accordance with the results of the follow-up study on patients from the International Pilot Study of Schizophrenia (IPSS), long lasting professional disintegration and psychiatric hospitalisation preceding index-admission were of special prognostic importance. However in contrast to this follow-up study, other psychopathological data, especially minus symptoms proved to be of considerable prognostic significance. As a result of stepwise multiple regression analyses, combinations of the 5 best characteristics for each outcome-criterion have been found which explain a significantly greater part of the variance than single characteristics.Keywords
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