Regulation of the fibronectin EDA exon alternative splicing. Cooperative role of the exonic enhancer element and the 5′ splicing site
Open Access
- 16 October 1998
- journal article
- research article
- Published by Wiley in FEBS Letters
- Vol. 437 (1-2), 137-141
- https://doi.org/10.1016/s0014-5793(98)01201-0
Abstract
Alternatively spliced exons generally contain weak splicing sites, and exonic and/or intronic regulatory elements recognised by trans‐acting auxiliary splicing factors. The EDA exon of the fibronecti...Keywords
This publication has 45 references indexed in Scilit:
- Interaction of U2AF 65 RS Region with Pre-mRNA of Branch Point and Promotion Base Pairing with U2 snRNAScience, 1996
- The splicing factor U2AF35 mediates critical protein-protein interactions in constitutive and enhancer-dependent splicing.Genes & Development, 1996
- Alternative Splicing of Fibronectin—Many Different Proteins but Few Different FunctionsExperimental Cell Research, 1995
- Protein–protein interactions and 5'-splice-site recognition in mammalian mRNA precursorsNature, 1994
- Specific interactions between proteins implicated in splice site selection and regulated alternative splicingCell, 1993
- A splicing enhancer in the human fibronectin alternate ED1 exon interacts with SR proteins and stimulates U2 snRNP binding.Genes & Development, 1993
- Specific commitment of different pre-mRNAs to splicing by single SR proteinsNature, 1993
- U1 snRNP targets an essential splicing factor, U2AF65, to the 3' splice site by a network of interactions spanning the exon.Genes & Development, 1992
- A Sequential splicing mechanism promotes selection of an optimal exon by repositioning a downstream 5' splice site in preprotachykinin pre-mRNA.Genes & Development, 1990
- Regulation of sex-specific RNA splicing at the Drosophila doublesex gene: cis-acting mutations in exon sequences alter sex-specific RNA splicing patterns.Genes & Development, 1990