AMP‐activated protein kinase – development of the energy sensor concept
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Open Access
- 19 June 2006
- journal article
- review article
- Published by Wiley in The Journal of Physiology
- Vol. 574 (1), 7-15
- https://doi.org/10.1113/jphysiol.2006.108944
Abstract
The LKB1→AMPK cascade is switched on by metabolic stresses that either inhibit ATP production (e.g. hypoxia, hypoglycaemia) or that accelerate ATP consumption (e.g. muscle contraction). Any decline i...Keywords
This publication has 96 references indexed in Scilit:
- Does AMP-activated Protein Kinase Couple Inhibition of Mitochondrial Oxidative Phosphorylation by Hypoxia to Calcium Signaling in O2-sensing Cells?Published by Elsevier ,2005
- The CREB coactivator TORC2 is a key regulator of fasting glucose metabolismNature, 2005
- Deficiency of LKB1 in skeletal muscle prevents AMPK activation and glucose uptake during contractionThe EMBO Journal, 2005
- Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinaseNature, 2002
- Role of AMP-activated protein kinase in mechanism of metformin actionJournal of Clinical Investigation, 2001
- Cell Cycle Regulation via p53 Phosphorylation by a 5′-AMP Activated Protein Kinase Activator, 5-Aminoimidazole- 4-Carboxamide-1-β- -Ribofuranoside, in a Human Hepatocellular Carcinoma Cell LineBiochemical and Biophysical Research Communications, 2001
- Peutz-Jeghers syndrome is caused by mutations in a novel serine threoninekinaseNature Genetics, 1998
- Identification by amino acid sequencing of three major regulatory phosphorylation sites on rat acetyl‐CoA carboxylaseEuropean Journal of Biochemistry, 1988
- Activation of rat liver cytosolic 3-hydroxy-3-methylglutaryl Coenzyme A reductase kinase by adenosine 5′-monophosphateBiochemical and Biophysical Research Communications, 1985
- Modulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity with cAMP and with protein fractions of rat liver cytosolBiochemical and Biophysical Research Communications, 1973