Direct n.m.r. observation of cell-free conversion of (L-α-amino-δ-adipyl)-L-cysteinyl-D-valine into isopenicillin N

Abstract

Carbon-13 n.m.r. spectroscopy has been used to observe the efficient conversion of (L-α-amino-δ-adipyl)-L-cysteinyl-D-valine into isopenicillin N in cell-free extracts of Cephalosporium acremonium.