Changes in the nucleic acid content of ganglion cells during chromatolysis and after stimulation
- 1 September 1956
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 64 (1), 29-32
- https://doi.org/10.1042/bj0640029
Abstract
Total nucleic acid and deoxyribonucleic acid (DNA) were determined in the superior cervical ganglion of the rabbit after section of the postganglionic fibers, and after stimulation of the preganglionic fibers. The normal levels of total nucleic acid and DNA were 44 mg and 13 mg of nucleic acid P/100 g wet weight of tissue, respectively. Both increased after section of the postganglionic fibers, nucleic acid to 130 mg in 14 days, DNA to 50 mg. The main increase was presumably in the RNA fraction. After stimulation of the preganglionic fibers total nucleic acid remained unchanged but DNA increased markedly. Estimations of total nucleic acid and DNA content of the superior cervical ganglion and tlbial nerve of very immature rabbits are also reported.Keywords
This publication has 3 references indexed in Scilit:
- The nucleic acid content of peripheral nerve in degeneration and activityProceedings of the Royal Society of London. B. Biological Sciences, 1956
- Estimation of nucleic acids in tissue from the nervous systemBiochemical Journal, 1952
- Appendix—A note on the determination of deoxypentosenucleic acid and pentosenucleic acid in tissue from the nervous system by ultraviolet absorptionBiochemical Journal, 1952