COMPARISON OF THE ACTIVE TRANSPORT SYSTEMS FOR α-THIOETHYL- d -GLUCOPYRANOSIDE AND MALTOSE IN SACCHAROMYCES CEREVISIAE

Abstract

Okada, Hirosuke (University of Wisconsin, Madison), and H. O. Halvorson. Comparison of the active transport systems for α-thioethyl-d-glucopyranoside and maltose in Saccharomyces cerevisiae. J. Bacteriol. 86:966–970. 1963.—Inducible systems for the active transport of both maltose and α-thioethyl-d-glucopyranoside (α-TEG) have been described in strains of Saccharomyces cerevisiae. The properties of induction of the α-TEG-accumulating system were similar to other inducible systems in yeast: the differential rate of synthesis was constant, and induction was inhibited by amino acid analogues. At temperatures below 20 C, the temperature dependence of α-TEG accumulation in induced cells was identical to that in facilitated diffusion. From a survey of various inducers, a coordinate induction of both active-transport systems was observed. These findings led to the conclusion that in active transport a common inducible enzyme is coupled to both the α-TEG and maltose facilitated-diffusion systems.