In the interval from 1948 through 1964, 34 patients with carcinoma of the ureter were seen. Six of these patients were referred for radiation therapy. Of this number, two received postoperative radiotherapy following biopsy of nonresectable tumor, two received postoperative radiotherapy for extensive regional disease where complete surgical extirpation was not possible, and two received radiotherapy for proved recurrences of disease. Significant periods with the patient free from disease can be obtained when adequate radiation dosages are employed, with three of five patients surviving five years without evidence of recurrence. Radiation therapy should be employed in those patients in whom only biopsy is possible, for those patients with extensive regional disease where surgical extirpation is not complete, and for recurrences following definitive surgical management.