The Scaffold Protein Gravin (cAMP-dependent Protein Kinase-anchoring Protein 250) Binds the β2-Adrenergic Receptor via the Receptor Cytoplasmic Arg-329 to Leu-413 Domain and Provides a Mobile Scaffold during Desensitization
Open Access
- 1 June 2001
- journal article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 276 (26), 24005-24014
- https://doi.org/10.1074/jbc.m011199200
Abstract
No abstract availableKeywords
This publication has 13 references indexed in Scilit:
- The Full-Length, Cytoplasmic C-Terminus of the β2-Adrenergic Receptor Expressed in E. coli Acts as a Substrate for Phosphorylation by Protein Kinase A, Insulin Receptor Tyrosine Kinase, GRK2, but Not Protein Kinase C and Suppresses Desensitization when Expressed in VivoProtein Expression and Purification, 2000
- AKAP79 and the evolution of the AKAP modelFEBS Letters, 2000
- Gravin-mediated Formation of Signaling Complexes in β2-Adrenergic Receptor Desensitization and ResensitizationJournal of Biological Chemistry, 2000
- Assembly of an A kinase-anchoring protein–β 2 -adrenergic receptor complex facilitates receptor phosphorylation and signalingCurrent Biology, 2000
- Dynamic Complexes of β2-Adrenergic Receptors with Protein Kinases and Phosphatases and the Role of GravinPublished by Elsevier ,1999
- G Protein-coupled ReceptorsJournal of Biological Chemistry, 1998
- Role of Clathrin-mediated Endocytosis in Agonist-induced Down-regulation of the β2-Adrenergic ReceptorJournal of Biological Chemistry, 1998
- Protein Kinase C Deficiency Blocks Recovery from Agonist-induced DesensitizationJournal of Biological Chemistry, 1996
- Molecular Glue: Kinase Anchoring and Scaffold ProteinsCell, 1996
- Oligodeoxynucleotides antisense to mRNA encoding protein kinase A, protein kinase C, and beta-adrenergic receptor kinase reveal distinctive cell-type-specific roles in agonist-induced desensitization.Proceedings of the National Academy of Sciences, 1994