Rapid antibiotic susceptibility tests on Enterobacteriaceae by ATP bioluminescence
- 1 February 1988
- journal article
- research article
- Published by Microbiology Society in Journal of Medical Microbiology
- Vol. 25 (2), 95-99
- https://doi.org/10.1099/00222615-25-2-95
Abstract
The susceptibility of 76 clinical isolates of Enterobacteriaceae to ampicillin, piperacillin and gentamicin was assessed by ATP bioluminescence in a 4-h test. For most organisms tested (Escherichia, Klebsiella, Enterobacter and Serratia), there was good correlation with traditional MIC values estimated on 18-h cultures. However strains of Proteus mirabilis showed false resistance to the β-lactam agents with the ATP method; and concordance was achieved only after manipulation of the growth conditions. Our method is simpler than those described previously, though currently it is still labour-intensive and expensive.This publication has 6 references indexed in Scilit:
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