The opitz syndrome: A new designation for the clinically indistinguishable BBB and G syndromes
- 1 October 1987
- journal article
- research article
- Published by Wiley in American Journal of Medical Genetics
- Vol. 28 (2), 303-309
- https://doi.org/10.1002/ajmg.1320280207
Abstract
The BBB and G syndromes are multiple congenital anomaly (MCA) syndromes characterized by a developmental defect of the midline field. Prominent clinical manifestations are hypertelorism and, in males, hypospadias. Transmission is most likely autosomal dominant in both syndromes. Examination of two new cases and scrutiny of the literature led us to conclude that there are no discriminating qualitative differences between the two conditions. Therefore we propose that they both be designated by the common term “Opitz syndrome”.Keywords
This publication has 3 references indexed in Scilit:
- G syndrome (hypertelorism with esophageal abnormality and hypospadias, or hypospadias‐dysphagia, or “Opitz‐Frias” or “opitz‐G” syndrome)—perspective in 1987 and bibliographyAmerican Journal of Medical Genetics, 1987
- Phenotypic overlap of the BBB and G syndromesAmerican Journal of Medical Genetics, 1978
- The G and BBB syndromes: Case presentations, genetics, and nosologyAmerican Journal of Medical Genetics, 1978