Identification and molecular cloning of the human Blym transforming gene activated in Burkitt's lymphomas

Abstract
DNA of 6 Burkitt''s lymphoma cell lines [Raji, Namalwa, BJAB, CW678, EW36, MC116] contained an activated transforming gene detected by transfection of [mouse] NIH 3T3 cells. This gene was cloned from a recombinant library of Burkitt''s lymphoma DNA and identified as a human homologue of chicken Blym-1, the transforming gene detected by transfection of chicken B cell lymphoma DNA.