Experiments on the intracerebral implantation of embryo tissues in rats

Abstract

The technique and results of some exps. on the implantation of embryo tissues in the brains of rats are descr. The brain appears to be a highly favorable soil for such implants, in which cartilage, bone, hemopoietic bone-marrow, epidermis, mucosal epithelia, teeth, salivary gland tissue, and skeletal muscle grow readily and differentiate well. In the most successful implants the amount of growth approximates that of an intact animal, and the differentiation of the various tissues also proceeds at a nearly normal rate. Reactionary changes in the nervous tissue of the host are slight; and, in spite of extensive encroachment on the brain by the growing implants, the nervous functions and health of the host-rats are rarely affected. The method may well prove of wider value in the study of some of the problems of growth and differentiation.[long dash].