Some Alterations in Serum Enzymes in Progressive Muscular Dystrophy.

Abstract

Acid and alkaline phosphatases, transaminase, and aldolase were determined in sera of 8 children and 9 adults afflicted with progressive muscular dystrophy. There was no alteration in phosphatase activity. Aldolase was increased in both children and adults while transaminase was distinctly elevated only in children. The ratio of aldolase to transaminase activity in serum increased in muscular dystrophy. Results indicate that increased activities of both aldolase and transminase in progressive muscular dystrophy are derived from diseased muscle.