Variations in apolipoproteins B and A, during the course of myocardial infarction

Abstract

The plasma apolipoproteins B and AI, and plasma lipids and lipoproteins, were studied in fifteen patients with acute myocardial infarction. In the days immediately after acute infarction there was a decrease in total cholesterol, low density lipopro-tein-cholesterol, total apolipoprotein-B, low density lipoprotein apolipoprotein-B and high density lipoprotein apolipoprotein AI. High density lipoprotein-cholesterol remained unchanged. In the same period the total triglycerides, very low density lipoprotein-protein, very low density lipoprotein-cholesterol, very low density lipoprotein apolipoprotein-B and very low density lipoprotein apolipoprotein A_I were increased. A reduction of the apolipoprotein ratio CII/ CIII occurred after the acute phase. After 25–30 days all these values regained their baseline values.