Effects of Pentylenetrazol on Senile Patients

Abstract

AT the Long Island Hospital in Boston the patients are mainly chronically ill elderly people, many of whom suffer from cardiovascular disease and have a history of cerebral hemorrhage. Often, they are depressed, disorientated and confused. Thus they should be suitable subjects for analeptic therapy since they correspond in type to the patients in whom Chesrow et al.,¹ Fong,² Smigel and his associates,³ Seidel, Silver and Nagel,⁴ Jensen and Leiser⁵ and others have reported good results with oral administration of pentylenetrazol (Metrazol). Smigel and his co-workers also cited improved appetite, red-cell count and hemoglobin after the same form of treatment. . . .