Muehlberger,1in 1925, reported a series of ten cases of shoe dye poisoning, bringing the present total of all cases reported in medical literature up to fifty-eight. He entered exhaustively into an analysis of this subject, quoting all the published data. The additional and particular merit of his analysis, however, lies in the fact that, whereas the cases previously reported in the United States were due to nitrobenzene poisoning, of the ten recorded by him six were due to aniline, these being the first to be reported in this country. To the six I now add three that recently came under my observation. REPORT OF CASES Case 1. —A girl, aged 14, who left her home at noon in good health, two hours later suddenly developed severe frontal headache and became cyanotic. This was followed by slight nausea and drowsiness. When seen at the hospital in the evening, she