Conserved Helix 7 Tyrosine Acts as a Multistate Conformational Switch in the 5HT2C Receptor
Open Access
- 1 September 2002
- journal article
- Published by Elsevier
- Vol. 277 (39), 36577-36584
- https://doi.org/10.1074/jbc.m206223200
Abstract
No abstract availableKeywords
This publication has 68 references indexed in Scilit:
- Seven-transmembrane receptors: crystals clarifyTrends in Pharmacological Sciences, 2002
- Phe303 in TMVI of the α1B-Adrenergic Receptor Is a Key Residue Coupling TM Helical Movements to G-protein ActivationBiochemistry, 2001
- Control of Conformational Equilibria in the Human B2 Bradykinin ReceptorPublished by Elsevier ,2001
- An Activation Switch in the Ligand Binding Pocket of the C5a ReceptorPublished by Elsevier ,2001
- Initial sequencing and analysis of the human genomeNature, 2001
- Functionally Different Agonists Induce Distinct Conformations in the G Protein Coupling Domain of the β2Adrenergic ReceptorJournal of Biological Chemistry, 2001
- Mechanism of Constitutive Activation of the AT1 Receptor: Influence of the Size of the Agonist Switch Binding Residue Asn111Biochemistry, 1998
- Rhodopsin activation blocked by metal-ion-binding sites linking transmembrane helices C and FNature, 1996
- A Conserved NPLFY Sequence Contributes to Agonist Binding and Signal Transduction but Is Not an Internalization Signal for the Type 1 Angiotensin II ReceptorJournal of Biological Chemistry, 1995
- Cloning of the human serotonin 5-HT2 and 5-HT1C receptor subtypesBiochemical and Biophysical Research Communications, 1991