Stabilities of dried suspensions of influenza virus sealed in a vacuum or under different gases.
- 1 June 1969
- journal article
- Vol. 17 (6), 830-5
Abstract
Suspensions of purified influenza virus, dried to a 1.4% content of residual moisture by sublimation of ice in vacuo, were sealed in a vacuum or under different gases of high purity. The stabilities of the several preparations were determined by an accelerated storage test. Based on the times predicted for the dried preparations stored at different temperatures to lose 1 log of infectivity titer, the order of stabilities in relation to sealing in vacuum or under different gases was as follows: helium > hydrogen > vacuum > argon > nitrogen > oxygen > carbon dioxide.This publication has 11 references indexed in Scilit:
- Estimation of the Shelf Life of a Drug in Its Solid State. II. A Proposition for a New Kinetical Equation of Gas-Solid Reactions for Pharmaceutical SolidsCHEMICAL & PHARMACEUTICAL BULLETIN, 1968
- Estimation of the Shelf Life of a Drug in Its Solid State. I. An Application of Lacey's Theory to a Kinetic Analysis of an Air Oxidation of Ascorbic Acid in Its Solid StateCHEMICAL & PHARMACEUTICAL BULLETIN, 1968
- Stabilities of suspensions of viruses after freezing or drying by vacuum sublimation and storageCryobiology, 1967
- Freezing and freeze-drying of virusesCryobiology, 1967
- Effects of Freezing, Storage at Low Temperatures, and Drying by Sublimation in vacuo on the Activities of Measles VirusNature, 1964
- Quantitative Aspects of the Protection of Freeze-Dried Escherichia coli Against the Toxic Effect of OxygenJournal of General Microbiology, 1963
- Some factors affecting preservability of freeze-dried bacteriaEpidemiology and Infection, 1961
- The Effect of Oxygen on Freeze-dried Escherichia coliJournal of General Microbiology, 1961
- The influence of oxygen on irreversible denaturation of beta-lacto-globulin.1953