RELEASE OF GENETIC TRANSFORMING AGENT FROM PNEUMOCOCCAL CULTURES DURING GROWTH AND DISINTEGRATION

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Abstract
Genetic transformations of pneumococcus mediated by streptomycin-induced lysates were studied to gain some insight into the nature of freshly released transforming principle, and the influence of the physiologic state of the donor population on the transformation process. It was found that streptomycin could make the DNA of sensitive cells available for transformation of other cells.