Synthesis of 3-deoxy-3-fluoro-D-glucose 1- and 6-phosphates and their intreaction with phosphoglucomutase and UDPG-pyrophosphorylase

Abstract
3-Deoxy-3-fluoro-α-D-glucose 1-phosphate (3) and the corresponding 6-phosphate (6) have been synthesised and shown to be competitive inhibitors of phosphoglucomutase and UDPG-pyrophosphorylase.