On the Monoclonal Origin of Chronic Myelocytic Leukemia
Open Access
- 1 January 1974
- journal article
- Published by Japan Academy in Proceedings of the Japan Academy
- Vol. 50 (5-6), 381-385
- https://doi.org/10.2183/pjab1945.50.381
Abstract
A male patient with CML had an unusual No. 9 chromosome with a typical Ph1 chromosome translocation. This unusual No. 9 chromosome showed heteromorphism at the 9qh region and a missing band in the middle of its long arm. These characteristic features of the leukemic cells strongly support the monoclonal origin of CML.Keywords
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