The Comparative Effects of Penicillin, Bacitracin, Chloromycetin, Aureomycin, and Streptomycin on Experimental Dental Caries and on Certain Oral Bacteria in the Rat

Abstract

These antibiotics were studied for their effectiveness in reducing exptl. dental caries in the albino rat by adding them to a coarse particle diet. Penicillin at a concn. of ,50,000 units % was most effective followed by bacitracin (5000 units %), aureomycin, chloramphenicol, and streptomycin all at 50,000 ug. %. Studies of oral lactobacilli, streptococci, and conforms revealed no consistent changes relatable to the caries picture.