ADAPTATION OF BACILLUS MEGATHERIUM TO TERRAMYCIN (OXYTETRACYCLINE)
Open Access
- 20 March 1957
- journal article
- research article
- Published by Rockefeller University Press in The Journal of general physiology
- Vol. 40 (4), 547-563
- https://doi.org/10.1085/jgp.40.4.547
Abstract
B. megatherium cultures contain a few cells per hundred million which are able to grow in the presence of terramycin. Growth of the other cells is inhibited by the antibiotic with the result that the resistant cells overgrow the culture. The resistant cells are present in the culture, without contact with terramycin, and are able to grow in the presence of terramycin, without further modification. The resistant cells are mutants of sensitive cells.Keywords
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