Sex-linked Hydrocephalus: Report of a Family with 15 Affected Members

Abstract
A case of congenital hydrocephalus present in a family in which many males had previously been affected showed, on autopsy, a primary stenosis of the aqueduct of Sylvius. The pattern of inheritance was entirely consistent with recessive sex-linkage. The case appears very similar to that described by Bickers and Adams both in its morbid anatomy and its mechanism of transmission.