The Response of Neoplastic Renal Vessels to Epinephrine in Man

Abstract

By the use of selective renal arteriography, the normal vessels and the vessels supplying a hypernephroma of the kidney were delineated in vivo. Following the injection of 25 mlcrograms of epinephrine into the renal artery, there was cessation of flow through the vessels supplying normal parenchyma, while the tumor vessels were densely opacified, although at a slower rate than during the control study. This constitutes the first evidence in man that the response of neoplastic renal vessels to humoral stimuli differs from that of normal vessels.