In vitro blood–brain barrier permeability and cerebral endothelial cell uptake of the neuroprotective nitrone compound NXY-059 in normoxic, hypoxic and ischemic conditions
- 8 October 2002
- journal article
- Published by Elsevier in Brain Research
- Vol. 955 (1-2), 229-235
- https://doi.org/10.1016/s0006-8993(02)03469-8
Abstract
No abstract availableKeywords
This publication has 31 references indexed in Scilit:
- NXY-059, a Free Radical–Trapping Agent, Substantially Lessens the Functional Disability Resulting From Cerebral Ischemia in a Primate SpeciesStroke, 2001
- Neuroprotection by 2-h Postischemia Administration of Two Free Radical Scavengers, α-phenyl-n-tert-butyl-nitrone (PBN) and N-tert-butyl-(2-sulfophenyl)-nitrone (S-PBN), in Rats Subjected to Focal Embolic Cerebral IschemiaExperimental Neurology, 2000
- The effect of α‐phenyl‐tert‐butyl nitrone (PBN) on free radical formation in transient focal ischaemia measured by microdialysis and 3,4‐dihydroxybenzoate formationActa Physiologica Scandinavica, 2000
- In vitro model for evaluating drug transport across the blood–brain barrierAdvanced Drug Delivery Reviews, 1999
- Delayed Treatment with α-Phenyl-N-tert-butyl Nitrone (PBN) Attenuates Secondary Mitochondrial Dysfunction after Transient Focal Cerebral Ischemia in the RatNeurobiology of Disease, 1996
- Distribution of spin-trapping compounds in rat blood and brain: In vivo microdialysis determinationFree Radical Biology & Medicine, 1993
- Drug Transfer Across the Blood‐Brain Barrier: Correlation Between In Vitro and In Vivo ModelsJournal of Neurochemistry, 1992
- An Easier, Reproducible, and Mass‐Production Method to Study the Blood–Brain Barrier In VitroJournal of Neurochemistry, 1990
- HPLC procedure for the pharmacokinetic study of the spin-trapping agent, α-phenyl-N-tert-butyl nitrone (PBN)Free Radical Biology & Medicine, 1990
- Oxygen free radical involvement in ischemia and reperfusion injury to brainNeuroscience Letters, 1988