Effect of Ticlopidine on the Long-Term Patency of Saphenous-Vein Bypass Grafts in the Legs

Abstract

Optimal therapy to prevent late occlusion of arterial bypass grafts in the legs has not been determined. We assessed the effect of ticlopidine, an inhibitor of platelet aggregation, on the long-term patency of saphenous-vein bypass grafts for the treatment of peripheral vascular disease.