Host-dependent modification of bacteriophage T7 and SAMase-negative T3 derivatives affecting their adsorption ability
- 1 February 1977
- journal article
- research article
- Published by Springer Nature in Molecular Genetics and Genomics
- Vol. 153 (1), 107-110
- https://doi.org/10.1007/bf01036002
Abstract
When passaging phage T7 and SAMase-negative T3 mutants betweenE. coli strains with identical (EcoB) or without (EcoO) DNA host specificity, phenotypically a host-controlled modification and restriction is observed. This phenomenon is not due to “classical” modification and restriction of the bacteriophage DNA but depends on the reversibly altered adsorption capacity of the phages on the different host strains.Keywords
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