Thiotropocin, a new sulfur-containing 7-membered-ring antibiotic produced by a Pseudomonas sp.

Abstract

Thiotropocin, a new sulfur-containing 7-membered-ring antibiotic, was isolated from a culture broth of Pseudomonas sp. CB-104. The antibiotic occurs as orange or yellowish orange needles and has the molecular formula C8H4O3S2. It is active against gram-positive and gram-negative bacteria, some phytopathogens and mycoplasma.