In vitro metabolism of T-2 toxin.
- 1 February 1974
- journal article
- Vol. 27 (2), 423-4
Abstract
Incubation of T-2 toxin with the 9,000 x g supernatant fluid of both human and bovine liver homogenate resulted in conversion to a single, deacetylated product identified as HT-2 toxin. Metabolism is more rapid in human liver. HT-2 toxin was not produced when human plasma was the incubating medium nor was it produced by treatment of T-2 toxin with simulated gastric juice. T-2 toxin was stable in gastric juice for at least 1 h.This publication has 3 references indexed in Scilit:
- T-2 toxin as an emetic factor in moldy corn.1973
- Biological and chemical detection of trichothecene mycotoxins of Fusarium species.1973
- Chemical interconversion of T-2 and HT-2 toxins and related compoundsBiochemical and Biophysical Research Communications, 1971