C1 AND HUMAN PLATELETS .2. DETECTION BY IMMUNOLOGICAL METHODS AND ROLE
- 1 January 1976
- journal article
- research article
- Vol. 30 (4), 459-465
Abstract
A C1 [the 1st complement component] hemolytic activity was previously shown to be associated with platelets. The presence of C1 on human gel filtered platelets is confirmed by Ouchterlony analysis and platelet aggregation induced by anti-C1q [q fragment of C1] antisera. After cleavage of C1 by EDTA, platelet aggregation induced by aggregated IgG [immunoglobulin G] was decreased and was restored by the addition of C1. The possible role of C1 in human platelet aggregation induced by aggregated Ig or immune complexes is discussed.This publication has 18 references indexed in Scilit:
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