Ascorbic Acid: Cofactor in Rabbit Olfactory Preparations
- 29 August 1969
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 165 (3896), 901-902
- https://doi.org/10.1126/science.165.3896.901
Abstract
A stimulant-induced decrease in absorbance at 267 nanometers in preparations from rabbit olfactory epithelium requires ascorbic acid as a cofactor. Vitamin C is bound to proteins in the olfactory mucosa in vivo. When the stimulant. 3,7-dimethyl-6-octen-3-ol interacts with olfactory proteins, it triggers a change in protein conformation which renders ascorbic acid available for oxidation. The specific decrease in absorbance at 267 nanometers is produced when the "freed" ascorbic acid is oxidized.Keywords
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