Effects of pyridoxine and magnesium on autistic symptoms?Initial observations

Abstract

In an open trial, a heterogeneous group of 44 children with autistic symptoms were treated with large doses of vitamin B₆ and magnesium. Clinical improvement with worsening on termination of the trial was observed in 15 children. Thirteen responders and 8 nonresponders were retested in a 2-week, crossover, double-blind trial, and the responses to the open trial were confirmed.