Three-dimensional static displacement, stimulated echo NMR elasticity imaging
- 19 May 2000
- journal article
- research article
- Published by IOP Publishing in Physics in Medicine & Biology
- Vol. 45 (6), 1633-1648
- https://doi.org/10.1088/0031-9155/45/6/316
Abstract
This article presents a method for measuring three-dimensional mechanical displacement and strain fields using stimulated echo MRI. Additional gradient pulses encode internal displacements in response to an externally applied deformation. By limiting the mechanical transition to the stimulated echo mixing time, a more accurate static displacement measurement is obtained. A three-dimensional elasticity reconstruction within a region of interest having a uniform shear modulus along its boundary is performed by numerically solving discretized elasticity equilibrium equations. Data acquisition, strain measurements and reconstruction were performed using a silicone gel phantom containing an inclusion of known elastic properties. A comparison between two-dimensional and three-dimensional reconstructions from simulated and experimental displacement data shows higher accuracy from the three-dimensional reconstruction. The long-term objective of this work is to provide a method for remotely palpating and elastically quantitating manually inaccessible tissues.Keywords
This publication has 32 references indexed in Scilit:
- High-resolution tensor MR elastography for breast tumour detectionPhysics in Medicine & Biology, 2000
- DENSE: Displacement Encoding with Stimulated Echoes in Cardiac Functional MRIJournal of Magnetic Resonance, 1999
- Practical application of a scan‐rotate equalization geometry to mammographyMedical Physics, 1996
- Visualizing tissue compliance with MR imagingJournal of Magnetic Resonance Imaging, 1995
- Magnetic Resonance Elastography by Direct Visualization of Propagating Acoustic Strain WavesScience, 1995
- Tracking of cyclic motion with phase‐contrast cine MR velocity dataJournal of Magnetic Resonance Imaging, 1995
- Breast Self-Examination in Relation to the Occurrence of Advanced Breast CancerJNCI Journal of the National Cancer Institute, 1991
- Characterization of transmitted motion in fetal lung: Quantitative analysisMedical Physics, 1989
- Self examination of the breast: is it beneficial? Meta-analysis of studies investigating breast self examination and extent of disease in patients with breast cancer.BMJ, 1988
- Multi-planar image formation using NMR spin echoesJournal of Physics C: Solid State Physics, 1977