The Effect of Staphylococcal Enterotoxin upon the Frog, (Rana pipiens)

Abstract

Staphylococcal enterotoxins which gave positive results with the kitten test were capable of producing spasms when fed to frogs. It would appear from the results summarized in Table I, that the frog test was specific for no false positive reactions were noted. It is not possible to use a frog more than once when a positive reaction has been obtained and further study is in progress to determine the nature of the injury to the digestive mechanism.